Guangdong, China
Business Type:
Manufacturer/Factory
Management System Certification:
ISO 9001, GMP
OEM/ODM Service

Aicar, Peptides, Peptide manufacturer / supplier in China, offering 98% Purity Peptide Aicar Sarms White Solid Powder Raw Material 50mg/Vial, High Purity Oral Steroids Powder Oxandrin Bodybuilding for Muscle Growth, Customized Supply Mixed Finished Oil Vials Super Test 450 Muscle Growth and so on.

Diamond Member Since 2012
Audited Supplier
Supplier Homepage Products Bodybuilding Peptides 98% Purity Peptide Aicar Sarms White Solid Powder Raw Material 50mg/Vial

98% Purity Peptide Aicar Sarms White Solid Powder Raw Material 50mg/Vial

Get Latest Price
Min. Order / Reference FOB Price
1 g US $1-2/ g
Port: Hong Kong, Hong Kong
Production Capacity: 50000piece/Year
Payment Terms: L/C, T/T, D/P, Western Union, Paypal, Money Gram
Powder: Yes
Customized: Non-Customized
Certification: HSE, ISO 9001, USP, BP
Suitable for: Adult
State: Solid
Purity: >99%

You Might Also Like

Loading...

Basic Info

Model NO.
Aicar
Name
Aicar
Adipotide CAS
Aicar
Adipotide MW
3357.96
Adipotide Purity
97%
Trademark
PowerlifeNutrition
Transport Package
1kg/Aluminium Foil Bag or as Required
Specification
10grams
Origin
China
HS Code
9602001000
product  description
Quick Detail:
Acadesine
Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE 
CAS: 2627-69-2 
EINECS: 220-097-5 
Molecular Formula: C9H14N4O5 
Molecular Weight: 258.23 
Assay: 98% 
Apperance: White or off-white powder. 
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases


Functions:
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
 
AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathways.
 
 
Biological Activity:
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle. 
 
Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro. 
 
Our Service
Fast DeliveryDelivery within 24 hours upon receipt of your payment
Quality Quality can be promised. Hot sell to Worldwide
Payment TermsT/T Bank Transfer, Western Union, Paypal, Bitcoin and MoneyGram Available
Sample Sample available at any time
Tracking your order at any timeInform your order's further new situation at any time
PackageProfessional packing with professional materials

Our advantage
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
5. Service: Best Service with after-sales service and consultation

Send your message to this supplier

*From:
*To:
avatar Mr. Liang
*Message:

Enter between 20 to 4,000 characters.

This is not what you are looking for? Post a Sourcing Request Now